Corpus ID: 19347051

Acute generalized exanthematous pustulosis due to tetrazepam.

@article{Thomas2008AcuteGE,
  title={Acute generalized exanthematous pustulosis due to tetrazepam.},
  author={E. Thomas and T. Bell{\'o}n and P. Barranco and A. Padial and B. Tapia and E. Morel and J. Alves-Ferreira and M. Mart{\'i}n-Esteban},
  journal={Journal of investigational allergology & clinical immunology},
  year={2008},
  volume={18 2},
  pages={
          119-22
        }
}
Tetrazepam is a benzodiazepine that is widely used in Spain as a muscle relaxant, with occasional cutaneous side effects. We report a patient who developed a generalized pruriginous cutaneous reaction compatible with acute generalized exanthematous pustulosis (AGEP) due to tetrazepam. Patch tests with bromazepam, diazepam, and tetrazepam were negative at 48 and 72 hours; however, the tetrazepam patch showed a positive reaction at 10 days. Immunohistochemical studies revealed a mononuclear… Expand
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References

SHOWING 1-10 OF 23 REFERENCES
T-cell involvement in drug-induced acute generalized exanthematous pustulosis.
  • 333
  • Highly Influential
  • PDF
Acute generalized exanthematous pustulosis associated with pseudoephedrine
  • 53
Acute generalized exanthematous pustulosis. Analysis of 63 cases.
  • 589
Delayed cell‐mediated hypersensitivity to tetrazepam
  • 23
Stevens-Johnson syndrome from tetrazepam.
  • 20
Delayed hypersensitivity to tetrazepam
  • 16
Tetrazepam allergy detected by patch test
  • 33
Acute generalized exanthematous pustulosis.
  • 75
Tetrazepam allergy once more detected by patch test
  • 21
Tetrazepam drug sensitivity − usefulness of the patch test
  • 29
...
1
2
3
...