Acute exposure to ozone exacerbates acetaminophen-induced liver injury in mice.

@article{Aibo2010AcuteET,
  title={Acute exposure to ozone exacerbates acetaminophen-induced liver injury in mice.},
  author={Daher Ibrahim Aibo and Neil Patrick Birmingham and Ryan P Lewandowski and Jane F. Maddox and Robert A. Roth and Patricia E. Ganey and James G. Wagner and Jack R. Harkema},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2010},
  volume={115 1},
  pages={267-85}
}
Ozone (O(3)), an oxidant air pollutant in photochemical smog, principally targets epithelial cells lining the respiratory tract. However, changes in gene expression have also been reported in livers of O(3)-exposed mice. The principal aim of the present study was to determine if acute exposure to environmentally relevant concentrations of O(3) could cause exacerbation of drug-induced liver injury in mice. Overdose with acetaminophen (APAP) is the most common cause of drug-induced liver injury… CONTINUE READING
8 Citations
61 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 61 references

Similar Papers

Loading similar papers…