Acute exposure to AICAR increases glucose transport in mouse EDL and soleus muscle.

@article{Balon2001AcuteET,
  title={Acute exposure to AICAR increases glucose transport in mouse EDL and soleus muscle.},
  author={Thomas W. Balon and Arnie P Jasman},
  journal={Biochemical and biophysical research communications},
  year={2001},
  volume={282 4},
  pages={
          1008-11
        }
}
AMP-activated protein kinase (AMPK) may regulate a number of metabolic processes including glucose transport. 5-Aminoimidazole-4-carboxamideribonucleoside (AICAR), an AMPK activator, has been used to study the potential role of AMPK in rat skeletal muscle; however, its effects on glucose transport in mouse skeletal muscle are unknown. Incubation with 2 mM AICAR increased 2-deoxyglucose transport in EDL muscle from both rats and mice by 86 and 37%, respectively. In contrast, AICAR did not… CONTINUE READING
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