Acute experimental pancreatitis in rat induced by sodium taurocholic acid: objective quantification of pancreatic necrosis


Retrograde injection of 5% sodium taurocholic acid (TA) in Wistar rat pancreatic duct is followed by acute pancreatitis, resulting in 100% mortality within 36 h. Biochemical determinations show raised levels of amylase in ascites and blood. Necrosis has been measured using seven morphometric characteristics of pathological changes that add precise… (More)
DOI: 10.1007/BF02358801


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