Acute exercise reverses TRB3 expression in the skeletal muscle and ameliorates whole body insulin sensitivity in diabetic mice.

@article{Matos2010AcuteER,
  title={Acute exercise reverses TRB3 expression in the skeletal muscle and ameliorates whole body insulin sensitivity in diabetic mice.},
  author={Adriana Pereira Matos and Eduardo Rochete Ropelle and Jos{\'e} Rodrigo Pauli and Marisa J{\'a}dna Silva Frederico and Ricardo Aurino de Pinho and Licio A Velloso and Claudio Teodoro de Souza},
  journal={Acta physiologica},
  year={2010},
  volume={198 1},
  pages={61-9}
}
AIM TRB3 became of major interest in diabetes research when it was shown to interact with and inhibit the activity of Akt. Conversely, physical exercise has been linked to improved glucose homeostasis. Thus, the current study was designed to investigate the effects of acute exercise on TRB3 expression and whole body insulin sensitivity in obese diabetic mice. METHODS Male leptin-deficient (ob/ob) mice swam for two 3-h-long bouts, separated by a 45-min rest period. After the second bout of… CONTINUE READING
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