Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes.

@article{Kennedy1999AcuteEI,
  title={Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes.},
  author={Jonathan W Kennedy and Michael F. Hirshman and Ernest V. Gervino and Jeffrey V Ocel and Robert Armour Forse and S J Hoenig and Doron Aronson and Laurie J Goodyear and Edward S. Horton},
  journal={Diabetes},
  year={1999},
  volume={48 5},
  pages={1192-7}
}
Total GLUT4 content in skeletal muscle from individuals with type 2 diabetes is normal; however, recent studies have demonstrated that translocation of GLUT4 to the plasma membrane is decreased in response to insulin stimulation. It is not known whether physical exercise stimulates GLUT4 translocation in skeletal muscle of individuals with type 2 diabetes. Five subjects (two men, three women) with type 2 diabetes and five normal control subjects (5 men), as determined by a standard 75-g oral… CONTINUE READING
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