Acute exacerbations of chronic bronchitis: what role for the new fluoroquinolones?

@article{Obaji2001AcuteEO,
  title={Acute exacerbations of chronic bronchitis: what role for the new fluoroquinolones?},
  author={A Obaji and Sunit Sethi},
  journal={Drugs & aging},
  year={2001},
  volume={18 1},
  pages={
          1-11
        }
}
Acute exacerbations of chronic bronchitis (AECB) are a major cause of morbidity and mortality. Bacterial pathogens are implicated in about half the episodes of AECB. Empirical antibacterials have a significant benefit in AECB; however, several recent developments have considerably complicated antibacterial choice for this condition. New fluoroquinolone antibacterials introduced in the last decade are theoretically well suited for the treatment of AECB, as the in vitro antimicrobial spectrum of… CONTINUE READING