Acute ethanol decreases NMR relaxation times of water hydrogen protons in fish brain.

@article{Isobe1994AcuteED,
  title={Acute ethanol decreases NMR relaxation times of water hydrogen protons in fish brain.},
  author={Seiichiro Isobe and Carlton F. Hazlewood and Lalith K. Misra and William R. Klemm},
  journal={Alcohol},
  year={1994},
  volume={11 6},
  pages={571-6}
}
The traditional belief about ethanol's mechanism of action is based on ethanol's lipophilicity and capability to penetrate and disorder lipid bilayers. This traditional belief is now being supplanted by growing evidence that ethanol has relatively selective actions on certain synaptic receptors, such as those for NMDA, serotonin, and GABA. It was recently argued that these receptor specificities are secondary to a preferential ability of ethanol to displace membrane bound water in the domains… CONTINUE READING