Acute ethanol administration causes malformations but does not affect cranial morphometry in neonatal mice.

@article{Oyedele2008AcuteEA,
  title={Acute ethanol administration causes malformations but does not affect cranial morphometry in neonatal mice.},
  author={Olusegun Olufemi Oyedele and Beverley Kramer},
  journal={Alcohol},
  year={2008},
  volume={42 1},
  pages={21-7}
}
Ethanol is a known teratogen and has been implicated in the etiology of human fetal alcohol syndrome (FAS), which is characterized by distinct craniofacial abnormalities such as microcephaly, agnathia, and ocular aberrations. Attempts at quantifying the craniofacial anomalies arising from ethanol exposure have largely been limited to radiographic evaluation in postnatal rats. Such studies discount the role of the cranial soft tissue in the morphology of FAS. We present a study whose aim was to… CONTINUE READING