Acute electrophysiological effects of intravenous milnacipran, a new antidepressant agent.

@article{Caron1993AcuteEE,
  title={Acute electrophysiological effects of intravenous milnacipran, a new antidepressant agent.},
  author={J. Raymond Caron and Christian Libersa and Jean Hazard and D. Lacroix and E Facq and Laurence Gu{\'e}don-Moreau and V M Fautrez and A Solles and Christian Puozzo and Salem Kacet},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={1993},
  volume={3 4},
  pages={493-500}
}
Milnacipran is a new antidepressant agent selected from a series of cycloproprane derivatives. The aim of this study was to investigate the acute electrophysiological effects and the tolerance of intravenous administration of this drug in 10 patients without any abnormality as shown in an electrophysiological study done for various complaints. Milnacipran was given over a 30-min period at doses of 0.2 mg/kg (2 patients), 0.4 mg/kg (2 patients) and 0.8 mg/kg (6 patients). The most significant… CONTINUE READING