Acute effects of opioids on memory functions of healthy men and women

@article{Friswell2008AcuteEO,
  title={Acute effects of opioids on memory functions of healthy men and women},
  author={J. Hain Friswell and Caroline E Phillips and James Holding and Celia J. A. Morgan and Brigitta Brandner and H. Valerie Curran},
  journal={Psychopharmacology},
  year={2008},
  volume={198},
  pages={243-250}
}
IntroductionAlthough several psychotropic drugs can acutely induce an anterograde impairment of memory which impedes new learning, they do not produce retrograde impairments, reducing memory for information learned prior to the drug being administered. However, both anterograde and retrograde memory impairments have been reported following an acute dose of morphine in palliative care patients (Kamboj et al., Pain 117:388–395, 2005).ObjectiveThe present study was designed to determine: (1… 
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References

SHOWING 1-10 OF 34 REFERENCES
Effects of methadone on cognition, mood and craving in detoxifying opiate addicts: a dose-response study
TLDR
A single dose of methadone can induce episodic memory impairment in patients who have a history of heroin use averaging more than 10 years and such impairment can be avoided by giving methamphetamineadone in divided doses.
Concentration-related effects of morphine on cognition and motor control in human subjects.
  • B. Kerr, H. Hill, A. Mackie
  • Biology, Psychology
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
  • 1991
TLDR
It is demonstrated that morphine can interfere with cognitive and motor performance at plasma drug concentrations within the usual therapeutic range.
Characterizing the subjective, psychomotor, and physiological effects of oral oxycodone in non-drug-abusing volunteers
TLDR
Although oxycodone produced abuse liability-related subjective effects, it also produced unpleasant effects, a phenomenon the authors have observed in other opioid studies in non-drug-abusing volunteers.
Impaired neuropsychological performance in chronic nonmalignant pain patients receiving long-term oral opioid therapy.
μ-Opioid Receptor-Mediated Antinociceptive Responses Differ in Men and Women
TLDR
It is demonstrated that at matched levels of pain intensity, men and women during their follicular phase differ in the magnitude and direction of response of the μ-opioid system in distinct brain nuclei.
Within-subject comparison of the psychopharmacological profiles of oral oxycodone and oral morphine in non-drug-abusing volunteers
TLDR
The psychopharmacological profile of oxycodone and morphine at equimiotic doses had many similarities; however, differences were found in producing abuse liability-related and dysphoric effects.
Sex differences in opioid analgesia
...
1
2
3
4
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