Acute effects of hydroxyzine on nocturnal sleep and sleep tendency the following day: A C‐EEG study

@article{Alford1992AcuteEO,
  title={Acute effects of hydroxyzine on nocturnal sleep and sleep tendency the following day: A C‐EEG study},
  author={C. Alford and N. Rombaut and J. Jones and S. Foley and C. Idzikowski and I. Hindmarch},
  journal={Human Psychopharmacology: Clinical and Experimental},
  year={1992},
  volume={7}
}
The acute hypnotic effects of hydroxyzine 25 mg and 50 mg nocte, were examined in six male and six female volunteers. Continuous electrophysiological measures (C‐EEG) were taken to assess both nocturnal sleep and sleep tendency the following day. Both doses produced significant reductions in sleep onset latency and decreases in waking during sleep; reciprocal increases in sleep duration were also seen. Female subjects demonstrated a greater hypnotic response, including a dose‐dependent decrease… Expand
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