Acute effects of clomipramine and fluoxetine on dorsal periaqueductal grey-evoked unconditioned defensive behaviours of the rat

@article{Schenberg2002AcuteEO,
  title={Acute effects of clomipramine and fluoxetine on dorsal periaqueductal grey-evoked unconditioned defensive behaviours of the rat},
  author={Luiz Carlos Schenberg and Larissa Capucho and Ricardo Vatanabe and Leila Vargas},
  journal={Psychopharmacology},
  year={2002},
  volume={159},
  pages={138-144}
}
Rationale: Several antidepressants attenuate conditioned escape behaviours reinforced by the terminus of an electrical stimulus applied to the dorsal periaqueductal grey (DPAG). Objective: The present study examined whether the antidepressant and antipanic drugs clomipramine (CLM) and fluoxetine (FLX) also attenuate the DPAG-evoked unconditioned defensive… CONTINUE READING