Acute effects of an antiserum to luteinizing hormone on ovarian steroidogenesis in the pregnant rat.


Pregnant rats were injected s.c. at 09.00 h on day 8 of pregnancy (day 1 = sperm-positive vaginal smear) with either 0.2 or 0.5 ml equine antiserum to bovine LH (anti-LH) while control rats were injected with 0.5 ml normal horse serum (NHS). Rats were decapitated 1, 3, 6, 24 and 48 h later and serum was saved for radioimmunoassay of progesterone… (More)