Acute effects of acetazolamide (diamox) on plasma and urinary electrolytes of dogs with special reference to calcium.

  title={Acute effects of acetazolamide (diamox) on plasma and urinary electrolytes of dogs with special reference to calcium.},
  author={S. Freeman and A. B. Jacobsen},
  journal={The American journal of physiology},
  volume={191 2},
Administration of Diamox by ingestion or injection to adult fasting female dogs consistently produced an acute increase of approximately 1 mg % in the plasma concentration of calcium. At the same time there was an increase in the plasma phosphate and chloride concentration and a decrease in total plasma content of carbon dioxide of Diamox-infused dogs. Diamox did not affect the plasma concentration of calcium, chloride or bicarbonate if renal excretory function was abolished prior to its… Expand
15 Citations
It is demonstrated that intravenous chlorothiazide causes a significant increase in both phosphorus and uric acid clearances and an equivocal decrease in the clearance of diffusible calcium. Expand
Direct effects of glucagon on renal hemodynamics and excretion of inorganic ions.
The results support the conclusion that glucagon acts directly upon the renal tubule to decrease the reabsorption of Na, Cl, H2O, Ca, and Mg, and to decreases the “net” tubular re absorption of K. Expand
Role of Extracellular Fluid Volume Expansion and Diuretics in Renal Handling of Phosphate
One of the more remarkable functions of the kidney is maintenance of the constancy of the composition and volume (ECV) of the extracellular fluid. The understanding of the mechanisms involved in ECVExpand
Renal Excretion of Alkaline Earths**These studies have been supported by the National Institutes of Health (AM-02306 and GM-K3-2583).
Publisher Summary This chapter discusses well over 100 recent reports in which the renal handling of alkaline earths has been examined by modern physiological techniques, including micropuncture,Expand
Effectiveness of Insulin Therapy on Altered Renal Calcium Transport in Diabetic Rats
It is concluded that this biochemical mechanism, which possibly may be implicated in the pathophysiology of diabetic nephropathy, is clearly influenced by duration of insulin deficiency and not by the degree in hyperglycemia. Expand
Renal Calcium Metabolism
Although bone harbors almost all of the body stores of calcium, the kidneys serve as the regulator of calcium homeostasis. Calcium filtered at the glomerulus is extensively reabsorbed by proximalExpand
Effects of Diuretics on Renal Function
The sections in this article are: 1 Diuretic Effects on Renal Hemodynamics 1.1 Drugs That Primarily Alter Glomerular Function 1.2 Drugs That Primarily Alter Tubular Function 1.3 Expand
Effect of ionic substitutions on distal potential differences in rat kidney.
The data are consistent with the thesis that the peritubular cell membrane has a high and selective potassium permeability, whereas the luminal cell membrane is characterized by approximately equal permeabilities to sodium, potassium, and chloride. Expand
Calcium and the kidney.
  • F. Epstein
  • Chemistry, Medicine
  • Journal of chronic diseases
  • 1960
Acidosis and hypercalciuria: renal mechanisms affecting calcium, magnesium and sodium excretion in the sheep
1. Observations were made on the excretion of calcium and magnesium by the sheep's kidney following manipulation of the acid—base status.