Acute disseminated encephalomyelitis: current controversies in diagnosis and outcome
- Medicine, PsychologyJournal of Neurology
This review comprehensively evaluates the current knowledge and controversies that surround ADEM, with special consideration of the distinction between ADEM and other demyelinating diseases such as multiple sclerosis.
Pattern and Outcome of Acute Disseminated Encephalomyelitis ( ADEM ) 1
- Medicine, Psychology
The most common clinical features of ADEM in the community are fever, disturbed conscious level (DCL), motor system weakness and convulsions, and the most valuable tool in diagnosis is brain MRI, which is very important in the diagnosis, management and counseling of patients with ADEM.
Acute Disseminated Encephalomyelitis
- MedicineWhite Matter Diseases
In the absence of specific biologic markers, ADEM remains a diagnosis of exclusion and it is still based on clinical manifestations, imaging, and laboratory features.
Chapter 60 – Acute Disseminated Encephalomyelitis
- Medicine, Biology
The Spectrum of Acute Disseminated Encephalomyelitis and Mild Encephalopathy with Reversible Splenial Lesion
- Medicine, PsychologyCase reports in neurological medicine
A 22-year-old woman developing mild neurological signs after an upper tract infection had a post infectious encephalitis sharing clinical and imaging criteria for acute disseminated encephalomyelitis, and mild encephalopathy with reversible splenial lesion could be an alternate diagnosis for this subject.
Acute disseminated encephalomyelitis
- Medicine, PsychologyNeurology
The current knowledge on epidemiology, pathology, clinical presentation, neuroimaging features, CSF findings, differential diagnosis, therapy, and outcome is summarized, with a focus on recent advances and controversies.
Clinical and radiological features of recurrent demyelination following acute disseminated encephalomyelitis (ADEM).
- Medicine, PsychologyMultiple sclerosis and related disorders
Spinal Cord Involvement in MS and Other Demyelinating Diseases
- Medicine, BiologyBiomedicines
This review describes spinal cord involvement, and summarize clinical findings, MRI and diagnostic characteristics, as well as treatment options and prognostic implications in different demyelinating disorders including: multiple sclerosis (MS), neuromyelitis optica spectrum disorder, acute disseminated encephalomyELitis, anti-myelin oligodendrocyte glycoprotein antibody-associated disease, and glial fibrillary acidic protein IgG- associated disease.
Acute Disseminated Encephalomyelitis: Current Perspectives
- Medicine, BiologyChildren
An update based on current epidemiologic, clinical, radiological and immunopathological aspects and clinical outcome of acute disseminated encephalomyelitis is provided.
Acute Disseminated Encephalomyelitis with Prefrontal Cortex Involvement in a 9-Year-Old Child after COVID-19 Infection: A Case Report
- Medicine, PsychologyJournal of Pediatric Neurology
The rare co-occurring radiological findings of a child presenting with acute disseminated encephalomyelitis with a spinal cord and prefrontal cortex involvement after coronavirus disease 2019 (COVID-19) illness is presented.
SHOWING 1-10 OF 81 REFERENCES
Disseminated encephalomyelitis and multiple sclerosis: two different diseases – a critical review
- Medicine, PsychologyActa neurologica Scandinavica
Magnetic resonance imaging (MRI) is the best means of distinguishing between disseminated encephalomyelitis (DEM) and MS.
Acute disseminated encephalomyelitis: an acute hit against the brain
- MedicineCurrent opinion in neurology
Capitalizing on experience based on a large body of well characterized patient data collected both cross-sectionally and longitudinally, pharmacotherapy has been improved and mortality and comorbidities due to ADEM have been reduced.
Acute Disseminated Encephalomyelitis in Childhood: Epidemiologic, Clinical and Laboratory Features
- Medicine, BiologyThe Pediatric infectious disease journal
ADEM is a potentially severe demyelinating disorder likely to be increasingly diagnosed as more magnetic resonance imaging studies are performed on patients with acute encephalopathy, and further characterization of the central nervous system inflammatory response will be needed to understand ADEM pathogenesis.
Clinical and neuroradiologic features of acute disseminated encephalomyelitis in children
- Medicine, PsychologyNeurology
The authors suggest that a viral prodrome, early-onset ataxia, high lesion load on MRI, involvement of the deep gray matter, and absence of oligoclonal bands are more indicative of ADEM.
Paediatric acquired demyelinating syndromes: incidence, clinical and magnetic resonance imaging features
- MedicineMultiple sclerosis
A trend towards higher incidence rates of ADS in children of South Asian and Black ethnicity was observed compared with White children, and a number of MRI characteristics distinguished ADEM from CIS cases.
Acute disseminated encephalomyelitis in children.
The epidemiologic evidence from this study suggests an infectious cause for ADEM is most likely a difficult-to-diagnose winter/spring respiratory virus.
Clinical and diagnostic aspects of multiple sclerosis and acute monophasic encephalomyelitis in pediatric patients: a single centre prospective study
- Medicine, PsychologyMultiple sclerosis
A pattern of demographic, clinical, neuroimaging, and laboratory findings that can help to distinguish, at clinical onset, children suffering from ADEM from those who will develop MS is depicted.
Clinical and neuroradiological differences of paediatric acute disseminating encephalomyelitis with and without antibodies to the myelin oligodendrocyte glycoprotein
- Medicine, BiologyJournal of Neurology, Neurosurgery & Psychiatry
Patients with ADEM with MOG antibodies in this cohort had a uniform MRI characterised by large, bilateral and widespread lesions with an increased frequency of longitudinal extensive transverse myelitis and a favourable clinical outcome in contrast to children lacking MOG antibody.
Acute disseminated encephalomyelitis in children: a single institution experience of 28 patients.
- Medicine, PsychologyNeuropediatrics
Clinical, laboratory, and neuroimaging features, treatment and outcome of acute disseminated encephalomyelitis in Taiwanese children to compare with two series from United States of America and Japan are described.
Vasogenic edema characterizes pediatric acute disseminated encephalomyelitis
It is proposed that vasogenic edema is a reliable diagnostic sign of acute neuroinflammation in ADEM and an inverse and significant relationship between time and ADC value is found.