Acute disseminated encephalomyelitis: Treatment guidelines

@inproceedings{Alexander2011AcuteDE,
  title={Acute disseminated encephalomyelitis: Treatment guidelines},
  author={Mathew Alexander and Jagaralapudi Murali K Murthy},
  booktitle={Annals of Indian Academy of Neurology},
  year={2011}
}
Acute disseminated encephalomyelitis (ADEM) is a monophasic, postinfectious or postvaccineal acute infl ammatory demyelinating disorder of central nervous system (CNS).[1,2] The pathophysiology involves transient autoimmune response directed at myelin or other self-antigens, possibly by molecular mimicry or by nonspecifi c activation of autoreactive T-cell clones.[3] Histologically, ADEM is characterized by perivenous demyelination and infi ltration of vessel wall and perivascular spaces by… CONTINUE READING

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