Acute disseminated encephalomyelitis: Treatment guidelines

  title={Acute disseminated encephalomyelitis: Treatment guidelines},
  author={Mathew Alexander and Jagaralapudi Murali K Murthy},
  booktitle={Annals of Indian Academy of Neurology},
Acute disseminated encephalomyelitis (ADEM) is a monophasic, postinfectious or postvaccineal acute infl ammatory demyelinating disorder of central nervous system (CNS).[1,2] The pathophysiology involves transient autoimmune response directed at myelin or other self-antigens, possibly by molecular mimicry or by nonspecifi c activation of autoreactive T-cell clones.[3] Histologically, ADEM is characterized by perivenous demyelination and infi ltration of vessel wall and perivascular spaces by… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 17 extracted citations


Publications referenced by this paper.
Showing 1-10 of 117 references

The treatment of central pain. Neurological therapeutics: Principles and practice

  • RR Tasker, CP Watson
  • 2003
Highly Influential
17 Excerpts

Similar Papers

Loading similar papers…