Acute dietary PCPA treatment decreases the KD of brain [3H]5-HT binding in rainbow trout, Oncorhynchus mykiss, fed a high carbohydrate diet.

@article{Johnston1994AcuteDP,
  title={Acute dietary PCPA treatment decreases the KD of brain [3H]5-HT binding in rainbow trout, Oncorhynchus mykiss, fed a high carbohydrate diet.},
  author={Wendy L. Johnston and Niall Glanville},
  journal={Comparative biochemistry and physiology. Pharmacology, toxicology and endocrinology},
  year={1994},
  volume={107 3},
  pages={455-61}
}
Two experiments were conducted to determine the effect of dietary PCPA on brain [3H]5-HT binding in rainbow trout. [3H]5-HT binding was quantitatively similar to that observed in mammalian species. Dietary treatment with PCPA had no effect on the Bmax of [3H]5-HT binding in either experiment while the KD was decreased in Experiment 1. These results demonstrate that [3H]5-HT binding affinity is increased following short term inhibition of 5-HT synthesis by PCPA in rainbow trout. 

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…