Acute crack cocaine exposure induces genetic damage in multiple organs of rats

  title={Acute crack cocaine exposure induces genetic damage in multiple organs of rats},
  author={Eduardo Gregolin Moretti and Ver{\^o}nica Quispe Yujra and Samuel Rangel Cl{\'a}udio and Marcelo Jos{\'e} Dias Silva and Wagner Vilegas and Camilo Dias Seabra Pereira and Flavia de Oliveira and Daniel Araki Ribeiro},
  journal={Environmental Science and Pollution Research},
Crack cocaine is a very toxic product derived from cocaine. The aim of this study was to evaluate genetic damage in multiple organs of rats following acute exposure to crack cocaine. A total of 20 Wistar rats were distributed into four groups (n = 5), as follows: 0, 4.5, 9, and 18 mg/kg body weight (b.w.) of crack cocaine administered by intraperitoneal route (i.p.). All animals were killed 24 h after intraperitoneal (i.p.) injection. The results showed that crack cocaine increased the number… 
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