Acute cholestatic hepatitis induced by fenofibrate.

  title={Acute cholestatic hepatitis induced by fenofibrate.},
  author={D Hajdu and K Aiglov{\'a} and Ilona Vinklerov{\'a} and Karel Urb{\'a}nek},
  journal={Journal of clinical pharmacy and therapeutics},
  volume={34 5},
We report a case of acute liver injury probably due to fenofibrate. A 50-year-old female without a history of liver disease developed cholestatic hepatitis during her second week of fenofibrate treatment. Laboratory tests on admission showed serum bilirubin 534.0 mcmol/L (conjugated 444.0), alkaline phosphatase (AP) 8.76, gamma-glutamyl traspeptidase (GGT) 20.92, alanine aminotransferase (ALT) 2.6, aspartate aminotransferase (AST) 3.64 mckat/L. Fenofibrate withdrawal and ursodeoxycholic acid… CONTINUE READING