Acute chest syndrome in sickle cell disease: clinical presentation and course. Cooperative Study of Sickle Cell Disease.

Abstract

Acute chest syndrome (ACS) is an important cause of morbidity and mortality in sickle cell disease (SCD). Previous studies reported conflicting pictures of ACS making therapeutic interventions difficult. The Cooperative Study of Sickle Cell Disease prospectively followed 3,751 patients enrolled from birth to 66 years of age for ACS. Data on presenting signs… (More)

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@article{Vichinsky1997AcuteCS, title={Acute chest syndrome in sickle cell disease: clinical presentation and course. Cooperative Study of Sickle Cell Disease.}, author={Elliot P Vichinsky and Lori A. Styles and Luigi Colangelo and Edward Wright and Olagide Wagner de Castro and Bethany R Nickerson}, journal={Blood}, year={1997}, volume={89 5}, pages={1787-92} }