Acute cadmium exposure and ovarian steroidogenesis in cycling and pregnant rats.

@article{Piasek1994AcuteCE,
  title={Acute cadmium exposure and ovarian steroidogenesis in cycling and pregnant rats.},
  author={Martina Piasek and John W. Laskey},
  journal={Reproductive toxicology},
  year={1994},
  volume={8 6},
  pages={495-507}
}
The purpose of this study was to evaluate the effect(s) of acute in vivo cadmium (Cd) exposure on steroidogenesis in rat ovaries during different reproductive states. Sprague-Dawley rats were injected subcutaneously on the day of diestrus, or on day 7 or 16 of gestation with a single dose of 0, 3, or 5 mg Cd/kg bw, and evaluated 24 h later. Serum progesterone and estradiol concentrations were determined. Whole-ovary culture was used to evaluate Cd effects on the production of progesterone… CONTINUE READING

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