Acute arrhythmogenicity of first-dose chemotherapeutic agents in children.

Abstract

BACKGROUND Chemotherapeutic agents have been reported to cause severe arrhythmias and sudden death in the first 24 hr after administration. In this prospective study, we determined the magnitude of acute arrhythmogenicity of those agents in children. PROCEDURE Thirty-three patients with diverse malignancies (leukemia n = 16, Wilms tumor n = 3, brain tumor… (More)

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