Acute antibody-mediated rejection in paediatric renal transplant recipients

  title={Acute antibody-mediated rejection in paediatric renal transplant recipients},
  author={Birgitta Kranz and Reinhard Kelsch and Eberhard Kuwertz-Br{\"o}king and Verena Broecker and Heiner Hubert Wolters and Martin Konrad},
  journal={Pediatric Nephrology},
Acute antibody-mediated rejections (aAMR) after renal transplantation are defined by rapidly deteriorating graft function, detection of donor-specific antibodies (DSA) and characteristic histological features. In adults, anti-rejection strategies comprise intravenous immunoglobulin (IVIG), steroid pulses, plasmapheresis and rituximab. Data of children with aAMR are scarce. We report four episodes of aAMR in three children (aged 10, 10 and 11 years respectively) occurring early after renal… CONTINUE READING


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