Acute antibody-mediated rejection following heart transplantation.

  title={Acute antibody-mediated rejection following heart transplantation.},
  author={Walter E. Uber and Sally E. Self and Adrian B. Van Bakel and Naveen Pereira},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  volume={7 9},
Acute antibody-mediated rejection (AMR) in heart transplantation is often associated with hemodynamic compromise, and is associated with increased mortality and development of accelerated transplant coronary artery disease (TCAD). The diagnosis of AMR has historically been controversial and outcomes with aggressive immunosuppressive therapy including plasmapheresis and cyclophosphamide are poor. Advances in diagnostic techniques like the demonstration of immunopathologic evidence for antibody… CONTINUE READING
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