Acute anti-inflammatory effects of inhaled budesonide in asthma: a randomized controlled trial.

@article{Gibson2001AcuteAE,
  title={Acute anti-inflammatory effects of inhaled budesonide in asthma: a randomized controlled trial.},
  author={Peter G Gibson and Nicholas Saltos and K Fakes},
  journal={American journal of respiratory and critical care medicine},
  year={2001},
  volume={163 1},
  pages={32-6}
}
Corticosteroids can have acute effects on airway function and methacholine airway responsiveness in asthma as early as 6 h after dosing, suggesting there may be an acute anti-inflammatory effect of inhaled corticosteroid in asthma. This study aimed to determine the effects of a single dose of inhaled budesonide on sputum eosinophils and mast cells in adults with asthma, and to examine whether the mechanism of clearance of eosinophils was by apoptosis. A randomized, double-blind, placebo… CONTINUE READING