Acute and subchronic toxicity of 1,1-dichloro-1-fluoroethane (HCFC-141b).

@article{Brock1995AcuteAS,
  title={Acute and subchronic toxicity of 1,1-dichloro-1-fluoroethane (HCFC-141b).},
  author={William J. Brock and Henry J Trochimowicz and R J Millischer and Craig H. Farr and Tomohito Kawano and George M Rusch},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={1995},
  volume={33 6},
  pages={483-90}
}
The acute and subchronic toxicity of 1,1-dichloro-1-fluoroethane (HCFC-141b), a CFC alternative, was evaluated in several acute and subchronic studies to assist in establishing proper handling guides. Data from acute toxicity studies in rats and rabbits demonstrated that HCFC-141b has very low acute toxicity. HCFC-141b was not a skin irritant, but was a mild eye irritant, in rabbits and was not a skin sensitizer in guinea pigs. Skin application of HCFC-141b to rabbits at 2000 mg/kg body weight… CONTINUE READING