Acute and subchronic effects of Rimcazole (BW 234U), a potential antipsychotic drug, on A9 and A10 dopamine neurons in the rat.

@article{Piontek1986AcuteAS,
  title={Acute and subchronic effects of Rimcazole (BW 234U), a potential antipsychotic drug, on A9 and A10 dopamine neurons in the rat.},
  author={Johann Piontek and R. Y. Wang},
  journal={Life sciences},
  year={1986},
  volume={39 7},
  pages={
          651-8
        }
}
  • Johann Piontek, R. Y. Wang
  • Published 1986
  • Medicine
  • Life sciences
  • The effects of acute and subchronic Rimcazole administration on A9 and A10 dopamine (DA) neurons were examined using extracellular single cell recording techniques. Intravenous injections of Rimcazole did not prevent or reverse the inhibition of firing rates of DA cells produced by DA agonist apomorphine (APO). Single intraperitoneal injection of Rimcazole decreased the number of spontaneously active DA cells in A10, but not in A9; it had no effect on the firing rate of DA neurons in either A9… CONTINUE READING
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    References

    SHOWING 1-10 OF 16 REFERENCES
    Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons
    • L. Chiodo, B. Bunney
    • Biology, Medicine
    • The Journal of neuroscience : the official journal of the Society for Neuroscience
    • 1983
    • 648
    • PDF
    Catecholamines in the brain as mediators of amphetamine psychosis.
    • S. Snyder
    • Psychology, Medicine
    • Archives of general psychiatry
    • 1972
    • 407
    An anatomy of schizophrenia?
    • J. Stevens
    • Psychology, Medicine
    • Archives of general psychiatry
    • 1973
    • 699