Acute and subacute oral toxicity of Litsea elliptica Blume essential oil in rats

@article{Budin2012AcuteAS,
  title={Acute and subacute oral toxicity of Litsea elliptica Blume essential oil in rats},
  author={Siti Balkis Budin and Seri Masran Siti Nor Ain and Baharuddin Hj Omar and Izatus Shima Taib and Othman Hidayatulfathi},
  journal={Journal of Zhejiang University SCIENCE B},
  year={2012},
  volume={13},
  pages={783-790}
}
Litsea elliptica Blume has been traditionally used to treat headache, fever, and stomach ulcer, and has also been used as an insect repellent. The acute and subacute toxicities of L. elliptica essential oil were evaluated orally by gavage in female Sprague-Dawley rats. For the acute toxicity study, L. elliptica essential oil was administered in doses from 500 to 4 000 mg/kg (single dose), and in the subacute toxicity test, the following doses were used: 125, 250, and 500 mg/kg, for 28… CONTINUE READING