Acute and subacute effects of diazepam on psychomotor skills: interaction with alcohol.

@article{Palva1979AcuteAS,
  title={Acute and subacute effects of diazepam on psychomotor skills: interaction with alcohol.},
  author={Erkki Palva and Markku Linnoila and Ilkka Saario and Mauri J. Mattila},
  journal={Acta pharmacologica et toxicologica},
  year={1979},
  volume={45 4},
  pages={
          257-64
        }
}
  • Erkki Palva, Markku Linnoila, +1 author Mauri J. Mattila
  • Published 1979
  • Medicine, Chemistry
  • Acta pharmacologica et toxicologica
  • Effects of diazepam and alcohol on psychomotor skills were measured in two trials. In the first one, 200 healthy students volunteered for a double-blind single-dose study. Three doses of diazepam (5, 10 and 20 mg) and alcohol (0.5, 0.8 and 1.2 g/kg) were used alone and combined to construct dose-response graphs. All doses of alcohol impaired divided attention while co-ordinative skills were impaired by the 1.2 g/kg dose. Diazepam alone did not impair reactive or co-ordinative skills whereas the… CONTINUE READING

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