Acute and long-term effects of vasodilator therapy on resting and exercise hemodynamics and exercise tolerance.


The acute hemodynamic response to vasodilators in patients with chronic heart failure has been well characterized, but less is known about the long-term hemodynamic effects of vasodilator therapy. We measured hemodynamic variables at rest and during upright exercise in 11 patients during the initiation of therapy with oral hydralazine and sublingual… (More)

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