Acute and delayed implantation of positively charged 2-hydroxyethyl methacrylate scaffolds in spinal cord injury in the rat.

@article{Hejl2008AcuteAD,
  title={Acute and delayed implantation of positively charged 2-hydroxyethyl methacrylate scaffolds in spinal cord injury in the rat.},
  author={Ale{\vs} Hej{\vc}l and Lucie Urdz{\'i}kov{\'a} and Jiř{\'i} {\vS}ed{\'y} and Petr Lesn{\'y} and Martin Př{\'a}dn{\'y} and Jir{\'i} Mich{\'a}lek and Martin Burian and Milan H{\'a}jek and Josef Z{\'a}me{\vc}n{\'i}k and Pavla Jendelov{\'a} and Eva Sykov{\'a}},
  journal={Journal of neurosurgery. Spine},
  year={2008},
  volume={8 1},
  pages={67-73}
}
OBJECT Hydrogels are nontoxic, chemically inert synthetic polymers with a high water content and large surface area that provide mechanical support for cells and axons when implanted into spinal cord tissue. METHODS Macroporous hydrogels based on 2-hydroxyethyl methacrylate (HEMA) were prepared by radical copolymerization of monomers in the presence of fractionated NaCl particles. Male Wistar rats underwent complete spinal cord transection at the T-9 level. To bridge the lesion, positively… CONTINUE READING
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