Acute and chronic methylphenidate dose-response assessment on three adolescent male rat strains.

@article{Yang2006AcuteAC,
  title={Acute and chronic methylphenidate dose-response assessment on three adolescent male rat strains.},
  author={Pamela Yang and Alan C. Swann and Nachum Dafny},
  journal={Brain research bulletin},
  year={2006},
  volume={71 1-3},
  pages={301-10}
}
Methylphenidate (MPD), commonly known as Ritalin, is the most frequently prescribed drug to treat children and adults with attention deficit hyperactivity disorder (ADHD). Adolescence is a period of development involving numerous neuroplasticities throughout the central nervous system (CNS). Exposure to a psychostimulant such as MPD during this crucial period of neurodevelopment may cause transient or permanent changes in the CNS. Genetic variability may also influence these differences. Thus… CONTINUE READING

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