Acute and chronic effects of verapamil in patients with paroxysmal supraventricular tachycardia.

@article{Sakurai1983AcuteAC,
  title={Acute and chronic effects of verapamil in patients with paroxysmal supraventricular tachycardia.},
  author={Makoto Sakurai and Harumasa Yasuda and Noboru Kato and Akikazu Nomura and Masatoshi Fujita and Tomokazu Nishino and Kunio Fujita and Yasunori Koike and Hironori Saito},
  journal={American heart journal},
  year={1983},
  volume={105 4},
  pages={619-28}
}
Efficacy of acute intravenous verapamil, 10 mg, and chronic oral verapamil, 320 mg, daily were studied electrophysiologically in 15 patients with paroxysmal supraventricular tachycardia (PSVT). Plasma verapamil concentrations were measured concurrently. Both intravenous and oral verapamil significantly increased the AV node conduction time, the cycle length producing a Wenckebach period, and the refractory period of the AV node. These changes were reflected in changes in plasma verapamil… CONTINUE READING

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European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulación Cardiaca y Electrofisiologia (SOLAECE).

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology • 2017

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