Acute and chronic effects of endotoxin on cerebral circulation in lambs.

Abstract

The impact of endotoxemia on cerebral endothelium and cerebral blood flow (CBF) regulation was studied in conscious newborn lambs. Bacterial endotoxin [LPS, 2 microg/kg iv] was infused on 3 consecutive days. Cerebrovascular function was assessed by monitoring CBF and cerebral vascular resistance (CVR) over 12 h each day and by the endothelium-dependent… (More)
DOI: 10.1152/ajpregu.00398.2009

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@article{Feng2010AcuteAC, title={Acute and chronic effects of endotoxin on cerebral circulation in lambs.}, author={Susan Y S Feng and Thilini D Samarasinghe and David J. Phillips and Theodora Alexiou and Jacob H. Hollis and Victor Y.H. Yu and Adrian Mark Walker}, journal={American journal of physiology. Regulatory, integrative and comparative physiology}, year={2010}, volume={298 3}, pages={R760-6} }