Acute and chronic effects of angiotensin converting enzyme inhibitors on the essential hypertensive kidney

@article{Reams1990AcuteAC,
  title={Acute and chronic effects of angiotensin converting enzyme inhibitors on the essential hypertensive kidney},
  author={Garry P. Reams and John H. Bauer},
  journal={Cardiovascular Drugs and Therapy},
  year={1990},
  volume={4},
  pages={207-219}
}
The natural course of essential hypertensive renal disease is characterized by a slowly progressive impairment of renal function. Initially, the changes are functional and reversible; however, structural changes gradually occur, leading to hypertensive nephrosclerosis. Similarities exist between the early functional hemodynamic changes observed in the essential hypertensive kidney and the physiologic renal effects of angiotensin II. To the degree that the initial functional changes are the… CONTINUE READING