Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo

@inproceedings{SerranoPozo2017AcuteAC,
  title={Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo},
  author={Alberto Serrano-Pozo and Manuel A S{\'a}nchez-Garc{\'i}a and Antonio Heras-Garv{\'i}n and Rosana March-D{\'i}az and Victoria Navarro and Marisa Vizuete and Jos{\'e} L{\'o}pez-Barneo and Javier Vitorica and Alberto Pascual},
  booktitle={PloS one},
  year={2017}
}
BACKGROUND Recent epidemiological evidence has linked hypoxia with the development of Alzheimer disease (AD). A number of in vitro and in vivo studies have reported that hypoxia can induce amyloid-β peptide accumulation through various molecular mechanisms including the up-regulation of the amyloid-β precursor protein, the β-secretase Bace1, or the… CONTINUE READING