Acute and Chronic Pretreatment With Atenolol Attenuates Intestinal Ischemia and Reperfusion Injury in Hypercholesterolemic Rats.

@article{Ozturk2016AcuteAC,
  title={Acute and Chronic Pretreatment With Atenolol Attenuates Intestinal Ischemia and Reperfusion Injury in Hypercholesterolemic Rats.},
  author={Tülün Öztürk and Kamil Vural and İbrahim Tuğlu and Ahmet Var and Taner Kurdal and Işıl Aydemir},
  journal={Journal of cardiothoracic and vascular anesthesia},
  year={2016},
  volume={30 4},
  pages={
          985-92
        }
}
OBJECTIVE To evaluate the protective effects of preinjury atenolol (acute v chronic) on apoptosis, contractility, oxidative stress, and inflammatory markers in hypercholesterolemic rats undergoing intestinal ischemia-reperfusion (I/R) injury. DESIGN Prospective, experimental animal study. SETTING University laboratory. PARTICIPANTS Male Wistar rats (n = 32). INTERVENTIONS Rats were divided into the following 4 groups: 1 group was fed a normal diet (ND) (group ND+NoAT [no atenolol]), and… CONTINUE READING

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