Acute and Chronic Effects of Cannabinoids on Human Cognition—A Systematic Review
@article{Broyd2016AcuteAC, title={Acute and Chronic Effects of Cannabinoids on Human Cognition—A Systematic Review}, author={Samantha Broyd and Hendrika H. van Hell and Camilla Beale and Murat Y{\"u}cel and Nadia Solowij}, journal={Biological Psychiatry}, year={2016}, volume={79}, pages={557-567} }
448 Citations
The acute effects of cannabis on human executive function
- Biology, PsychologyBehavioural pharmacology
- 2018
It is suggested that cannabis use results in acute impairment of inhibition, with the strongest effects after pulmonary administration of higher doses of [INCREMENT]9-tetrahydrocannabinol.
Acute effects of partial CB1 receptor agonists on cognition – A meta-analysis of human studies
- Psychology, BiologyProgress in Neuro-Psychopharmacology and Biological Psychiatry
- 2021
The neuropsychopharmacology of cannabis: A review of human imaging studies
- Psychology, BiologyPharmacology & therapeutics
- 2019
The Effects of Cannabinoids on Executive Functions: Evidence from Cannabis and Synthetic Cannabinoids—A Systematic Review
- Medicine, BiologyBrain sciences
- 2018
Both pre-clinical and clinical studies demonstrated an association between synthetic cannabinoids and executive-function impairment either after acute or repeated consumptions of these drugs.
Neurocognitive consequences of chronic cannabis use: a systematic review and meta-analysis
- Psychology, BiologyNeuroscience & Biobehavioral Reviews
- 2020
Therapeutic Effects of Prolonged Cannabidiol Treatment on Psychological Symptoms and Cognitive Function in Regular Cannabis Users: A Pragmatic Open-Label Clinical Trial
- Psychology, MedicineCannabis and cannabinoid research
- 2018
Prolonged CBD treatment appears to have promising therapeutic effects for improving psychological symptoms and cognition in regular cannabis users, and it is suggested that CBD may be a useful adjunct treatment for cannabis dependence.
Cannabis and Cognitive Functioning: From Acute to Residual Effects, From Randomized Controlled Trials to Prospective Designs
- Psychology, BiologyFrontiers in Psychiatry
- 2021
The association between cannabis and cognition is likely explained by common antecedents, such that genetic and shared environment factors predispose individuals to both cannabis use and cognitive deficits, and to a lesser degree, neurotoxic effects.
References
SHOWING 1-10 OF 163 REFERENCES
The acute effects of cannabinoids on memory in humans: a review
- Biology, PsychologyPsychopharmacology
- 2006
This profile of effects suggests that cannabinoids impair all stages of memory including encoding, consolidation, and retrieval, and that cannabinoids increase intrusion errors with the inhaled and intravenous route and correspond to peak drug levels.
Acute and non-acute effects of cannabis on human memory function: a critical review of neuroimaging studies.
- Psychology, BiologyCurrent pharmaceutical design
- 2014
Results of neuroimaging studies that investigated acute and non-acute effects of cannabis on human learning and memory function, both in adults and in adolescents show that cannabis use is associated with a pattern of increased activity and a higher level of deactivation in different memory-related areas.
[Cognitive abnormalities and cannabis use].
- Biology, PsychologyRevista brasileira de psiquiatria
- 2010
The endogenous cannabinoid system is involved in regulatory neural mechanisms that modulate processes underlying a range of cognitive functions that are impaired by cannabis, and defects in human users most likely reflect neuroadaptations and altered functioning of the endogenous cannabinoids system.
Neuroimaging studies of acute effects of THC and CBD in humans and animals: a systematic review.
- Medicine, BiologyCurrent pharmaceutical design
- 2014
Functional neuroimaging studies have provided extensive evidence for the acute modulation of brain function by cannabinoids, but further studies are needed in order to understand the neural mechanisms underlying these effects.
An Evidence-Based Review of Acute and Long-Term Effects of Cannabis Use on Executive Cognitive Functions
- Biology, PsychologyJournal of addiction medicine
- 2011
The research on the acute, residual, and long-term effects of cannabis use on executive functions is reviewed and the implications for treatment are discussed.
Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being
- Psychology, MedicinePsychological Medicine
- 2011
CBD attenuates the psychotic-like effects of cannabis over time in recreational users, and raises concerns for the harms stemming from use of varieties such as ‘skunk’ (sensimillia), which lack any CBD but currently dominate the supply of cannabis.
Residual effects of cannabis use on neurocognitive performance after prolonged abstinence: a meta-analysis.
- Psychology, BiologyExperimental and clinical psychopharmacology
- 2012
Overall, these meta-analyses demonstrate that any negative residual effects on neurocognitive performance attributable to either cannabis residue or withdrawal symptoms are limited to the first 25 days of abstinence and there was no evidence for enduring negative effects of cannabis use.
Gone to Pot – A Review of the Association between Cannabis and Psychosis
- Psychology, MedicineFront. Psychiatry
- 2014
The evidence indicates that cannabis may be a component cause in the emergence of psychosis, and this warrants serious consideration from the point of view of public health policy.
Cognitive functioning of long-term heavy cannabis users seeking treatment.
- Psychology, MedicineJAMA
- 2002
It is confirmed that long-term heavy cannabis users show impairments in memory and attention that endure beyond the period of intoxication and worsen with increasing years of regular cannabis use.
Cannabis use, cognitive performance and mood in a sample of workers
- PsychologyJournal of psychopharmacology
- 2006
Cannabis use was associated with impairment in both cognitive function and mood, though cannabis users reported no more workplace errors than controls, and users experienced working memory problems at the start, and psychomotor slowing and poorer episodic recall at the end of the working week.