Acute administration of corticoids: a new and peculiar stimulus of growth hormone secretion in man.

@article{Casanueva1990AcuteAO,
  title={Acute administration of corticoids: a new and peculiar stimulus of growth hormone secretion in man.},
  author={F. F. Casanueva and B Burguera and C Muruais and Carlos Di{\'e}guez},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1990},
  volume={70 1},
  pages={234-7}
}
It is widely accepted that chronic administration of corticoids in man inhibits the GH response to all of the stimuli tested so far. To study the action of corticoids administered acutely, several dexamethasone challenge tests were performed, after which GH levels were measured for 7 h. In eight volunteers, administration of 4 mg dexamethasone (Dex), iv, induced a clear-cut GH release compared with saline administration. The secretion followed an unusual pattern; basal GH levels (1.5 +/- 0.1… CONTINUE READING