Acute Respiratory Distress Syndrome: Advances in Diagnosis and Treatment

@article{Fan2018AcuteRD,
  title={Acute Respiratory Distress Syndrome: Advances in Diagnosis and Treatment},
  author={Eddy Fan and Daniel Brodie and Arthur S Slutsky},
  journal={JAMA},
  year={2018},
  volume={319},
  pages={698–710}
}
Importance Acute respiratory distress syndrome (ARDS) is a life-threatening form of respiratory failure that affects approximately 200 000 patients each year in the United States, resulting in nearly 75 000 deaths annually. [] Key Method Evidence Review We searched MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews from 2012 to 2017 focusing on randomized clinical trials, meta-analyses, systematic reviews, and clinical practice guidelines.

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Prolonged corticosteroid treatment in early ARDS improved the survival outcomes and several endpoints such as ventilator-free days and adverse events were set as the secondary outcomes.
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In the general population, the incidence and mortality associated with ARDS over the last two decades have steadily declined in parallel with optimized approaches to pneumonia and other underlying causes of ARDS as well as increased utilization of multimodal treatment strategies that include lung-protective ventilation.
Early Improvement of Acute Respiratory Distress Syndrome in Patients With COVID-19 in the Intensive Care Unit: Retrospective Analysis
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A new subphenotype of ARDS—eiARDS—in patients with COVID-19 was identified and the stratified management of patients based on eiARDS or age is highly recommended.
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