Acute Opiate Overdose: An Update on Management Strategies in Emergency Department and Critical Care Unit

  title={Acute Opiate Overdose: An Update on Management Strategies in Emergency Department and Critical Care Unit},
  author={Rukma Parthvi and Abhinav Agrawal and Sameer Khanijo and Adey Tsegaye and Arunabh Talwar},
  journal={American Journal of Therapeutics},
Background: Opioids are natural, semisynthetic, or synthetic substances that act on opioid receptors in the central nervous system. Clinically, they are prescribed for pain management. Opioid overdose (OOD) occurs when the central nervous system and respiratory drive are suppressed because of excessive consumption of the drug. Symptoms of OOD include drowsiness, slow breathing, pinpoint pupils, cyanosis, loss of consciousness, and death. Due to their addictive potential and easy accessibility… 
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