Acute Modulation of Mycobacterial Cell Envelope Biogenesis by Front-Line Tuberculosis Drugs.

@article{RodriguezRivera2018AcuteMO,
  title={Acute Modulation of Mycobacterial Cell Envelope Biogenesis by Front-Line Tuberculosis Drugs.},
  author={Frances P Rodriguez-Rivera and Xiaoxue Zhou and Julie A. Theriot and Carolyn R Bertozzi},
  journal={Angewandte Chemie},
  year={2018},
  volume={57 19},
  pages={5267-5272}
}
Front-line tuberculosis (TB) drugs have been characterized extensively in vitro and in vivo with respect to gene expression and cell viability. However, little work has been devoted to understanding their effects on the physiology of the cell envelope, one of the main targets of this clinical regimen. Herein, we use metabolic labeling methods to visualize… CONTINUE READING