Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance.

@article{Bailey2010AcuteLS,
  title={Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance.},
  author={Stephen J Bailey and Paul G. Winyard and Anni Vanhatalo and Jamie R. Blackwell and Fred J. DiMenna and Daryl P. Wilkerson and Andrew M. Jones},
  journal={Journal of applied physiology},
  year={2010},
  volume={109 5},
  pages={
          1394-403
        }
}
It has recently been reported that dietary nitrate (NO(3)(-)) supplementation, which increases plasma nitrite (NO(2)(-)) concentration, a biomarker of nitric oxide (NO) availability, improves exercise efficiency and exercise tolerance in healthy humans. We hypothesized that dietary supplementation with L-arginine, the substrate for NO synthase (NOS), would elicit similar responses. In a double-blind, crossover study, nine healthy men (aged 19-38 yr) consumed 500 ml of a beverage containing 6 g… 
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No effect of acute l-arginine supplementation on O2 cost or exercise tolerance
TLDR
In conclusion, acute dietary supplementation with ARG or ARG + CHO did not alter biomarkers of NO synthesis, O2 cost of exercise or exercise tolerance in healthy subjects.
l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
TLDR
It is suggested that short-term Cit, but not Arg, supplementation can improve blood pressure, V̇o2 kinetics, and exercise performance in healthy adults.
Acute L-Arginine supplementation does not increase nitric oxide production in healthy subjects
Dietary supplements containing L-arginine have been marketed with the purpose of increasing vasodilatation, and thus, blood and oxygen supply to the exercising muscle. The present study evaluated the…
Acute l-arginine supplementation increases muscle blood volume but not strength performance.
  • T. Alvares, C. A. Conte, +4 authors P. Gomes
  • Medicine
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
  • 2012
TLDR
It is found that acute L-arg supplementation increases Mbv during recovery from sets of resistance exercise with no increase in strength performance, and it is still premature to recommend nutritional supplements containing L- arg as an ergogenic aid to increase muscle strength during resistance training in healthy subjects.
Acute Effects of L-Arginine Supplementation on Oxygen Consumption Kinetics and Muscle Oxyhemoglobin and Deoxyhemoglobin during Treadmill Running in Male Adults
TLDR
The results do not support the use of L-arginine as an ergogenic aid for running performance in young healthy males because ARG supplementation does not improve physiological responses associated with oxygen cost and NIRS variables during running treadmill tests.
L-Arginine Supplementation and Nitric Oxide Production: No Additional Effect When Associated to Exercise
TLDR
L-arginine supplementation was unable to increase the effects of exercise on nitric oxide production and did not improve the metabolic responses to exercise in runners.
L-Arginine as a Potential Ergogenic Aidin Healthy Subjects
TLDR
It is still premature to recommend dietary supplements containing L-arginine as an ergogenic aid for healthy physically active subjects, as low oral doses (20 g) are well tolerated and clinical side effects are rare in healthy subjects.
L-Arginine supplementation improves antioxidant defenses through L-arginine/nitric oxide pathways in exercised rats.
TLDR
The data demonstrate that l-Arg supplementation effectively reduces the exercise-induced imbalance between oxidative stress and antioxidant defense capacity, and this modulation is likely mediated through the l- Arg/NO pathways.
The acute effects of L-arginine on hormonal and metabolic responses during submaximal exercise in trained cyclists.
TLDR
The acute ingestion of L-arginine did not alter any hormonal, metabolic, or cardio-respiratory responses during submaximal exercise except for a small but significant increase in glycerol at the 45-min time point and a reduction in fat oxidation at the start of exercise.
Dietary nitrate improves muscle but not cerebral oxygenation status during exercise in hypoxia.
TLDR
Short-term dietary nitrate supplementation improves arterial and muscle oxygenation status but not cerebral oxygenationstatus during exercise in severe hypoxia, associated with improved exercise tolerance against the background of a similar incidence of AMS.
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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