Acute Gastrointestinal Bleeding

  title={Acute Gastrointestinal Bleeding},
  author={Meeta Prasad Kerlin and Jeffrey L. Tokar},
  journal={Annals of Internal Medicine},
Acid-base balance has been studied in 21 patients with acute upper gastrointestinal bleeding. A low plasma bicarbonate concentration was found in nine patients, accompanied in each case by a base deficit of more than 3 mEq/litre, indicating a metabolic acidosis. Three patients had a low blood pH. Hyperlactataemia appeared to be a major cause of the acidosis. This was not accompanied by a raised blood pyruvate concentration. The hyperlactataemia could not be accounted for on the basis of… Expand
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