Acute Ethanol Poisoning and the Ethanol Withdrawal Syndrome

  title={Acute Ethanol Poisoning and the Ethanol Withdrawal Syndrome},
  author={B. Adinoff and G. Bone and M. Linnoila},
  journal={Medical Toxicology and Adverse Drug Experience},
  • B. Adinoff, G. Bone, M. Linnoila
  • Published 1988
  • Chemistry, Medicine
  • Medical Toxicology and Adverse Drug Experience
  • SummaryEthanol, a highly lipid-soluble compound, appears to exert its effects through interactions with the cell membrane. Cell membrane alterations indirectly affect the functioning of membrane-associated proteins, which function as channels, carriers, enzymes and receptors. For example, studies suggest that ethanol exerts an effect upon the γ-aminobutvric acid (GABA)-benzodiazepine-chloride ionophore receptor complex, thereby accounting for the biochemical and clinical similarities between… CONTINUE READING
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