Acute Effect of a Glucocorticoid on Normal Human Sleep

@article{Gillin1972AcuteEO,
  title={Acute Effect of a Glucocorticoid on Normal Human Sleep},
  author={J. Christian Gillin and L S Jacobs and David H. Fram and Frederick Snyder},
  journal={Nature},
  year={1972},
  volume={237},
  pages={398-399}
}
ELECTROENCEPHALOGRAPHIC studies of sleep suggest that the magnitude of sleep disturbances in depressed and schizophrenic subjects varies with the degree of psychic turmoil1–6. Psychoendocrine studies of psychiatric patients have suggested that adrenal cortical steroid excretion is elevated with subjective distress7–13. Some endocrine studies have shown that nocturnal secretion of adrenal cortical steroids is elevated at least part of the time in psychiatric patients14–17. We have undertaken to… CONTINUE READING

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