Acute Complications of Preeclampsia

@article{Norwitz2002AcuteCO,
  title={Acute Complications of Preeclampsia},
  author={Errol R. Norwitz and Chaur-Dong Hsu and John T. Repke},
  journal={Clinical Obstetrics and Gynecology},
  year={2002},
  volume={45},
  pages={308-329}
}
Preeclampsia is an idiopathic multisystem disorder specific to human pregnancy and the puerperium. More precisely, it is a disease of the placenta, because it has also been described in pregnancies where there is trophoblast but no fetal tissue (complete molar pregnancies). Although the pathophysiology of preeclampsia is poorly understood, it is clear that the blueprint for its development is laid down early in pregnancy. It has been suggested that the pathologic hallmark is a complete or… 
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References

SHOWING 1-10 OF 130 REFERENCES
Acute renal failure in preeclampsia-eclampsia.
TLDR
The associationPE-E + AP seems to be a particularly unfavorable prognostic sign for the kidney owing to the contribution of additional damage mechanisms furnished by AP, while PE-E itself prepares the ground for AP.
Blindness associated with preeclampsia and eclampsia.
Ocular manifestations of preeclampsia.
TLDR
None of the patients showed background changes of hemorrhages, cotton-wool spots, and exudates, or evidence of choroidal ischemia, and the role of the ophthalmologist in the diagnosis and management of preeclampsia appears to be limited.
The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): much ado about nothing?
  • B. Sibai
  • Medicine
    American journal of obstetrics and gynecology
  • 1990
Pregnancy complicated by preeclampsia-eclampsia with the syndrome of hemolysis, elevated liver enzymes, and low platelet count: how rapid is postpartum recovery?
TLDR
It is concluded that the platelet count and LDH serum concentration, as indicators of HELLP severity and recovery, are clinically useful tools and that a more protracted postpartum recovery period should be expected for progressively severe expressions of HELLp syndrome.
Postpartum eclampsia: A recurring perinatal dilemma
...
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