Acute Bacterial and Viral Meningitis

@article{Bartt2012AcuteBA,
  title={Acute Bacterial and Viral Meningitis},
  author={Russell E. Bartt},
  journal={Continuum: Lifelong Learning in Neurology},
  year={2012},
  volume={18},
  pages={1255–1270}
}
  • R. Bartt
  • Published 1 December 2012
  • Medicine
  • Continuum: Lifelong Learning in Neurology
Purpose of Review: Most cases of acute meningitis are infectious and result from a potentially wide range of bacterial and viral pathogens. The organized approach to the patient with suspected meningitis enables the prompt administration of antibiotics, possibly corticosteroids, and diagnostic testing with neuroimaging and spinal fluid analysis. Recent Findings: Acute meningitis is infectious in most cases and caused by a potentially wide range of bacterial and viral pathogens. Shifts in the… 

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References

SHOWING 1-10 OF 19 REFERENCES
Epidemiology, Diagnosis, and Antimicrobial Treatment of Acute Bacterial Meningitis
TLDR
The changing epidemiology of bacterial meningitis in the United States and throughout the world is described by reviewing the global changes in etiological agents followed by specific microorganism data on the impact of the development and widespread use of conjugate vaccines.
Viral meningitis.
  • K. R. Ratzan
  • Medicine, Biology
    The Medical clinics of North America
  • 1985
Community-Acquired Bacterial Meningitis: Risk Stratification for Adverse Clinical Outcome and Effect of Antibiotic Timing
TLDR
A prognostic model was developed that stratified patients into three levels of risk (low, intermediate, and high) for adverse clinical outcome and the prediction accuracy of the prognosticmodel was assessed.
Dexamethasone in adults with bacterial meningitis
TLDR
A prospective, randomized, double-blind, multicenter trial of adjuvant treatment with dexamethasone, as compared with placebo, in adults with acute bacterial meningitis.
Clinical features and prognostic factors in adults with bacterial meningitis.
TLDR
The mortality associated with bacterial meningitis remains high, and the strongest risk factors for an unfavorable outcome are those that are indicative of systemic compromise, a low level of consciousness, and infection with S. pneumoniae.
Lumbar puncture in pediatric bacterial meningitis: defining the time interval for recovery of cerebrospinal fluid pathogens after parenteral antibiotic pretreatment.
TLDR
It is demonstrated that CSF sterilization may occur more rapidly after initiation of parenteral antibiotics than previously suggested, with complete sterilization of meningococcus within 2 hours and the beginning of sterilizing of pneumococcus by 4 hours into therapy.
Bacterial meningitis in the United States in 1995. Active Surveillance Team.
TLDR
Bacterial meningitis in the United States is now a disease predominantly of adults rather than of infants and young children, largely as a result of a 94 percent reduction in the number of cases of H. influenzaeMeningitis due to vaccine-related decline.
Bacterial meningitis in the United States, 1998-2007.
TLDR
The rates of bacterial meningitis have decreased since 1998, but the disease still often results in death, and the burden of bacterialMeningitis is now borne more by older adults.
Bacterial meningitis in the United States, 1986: report of a multistate surveillance study. The Bacterial Meningitis Study Group.
TLDR
A prospective, laboratory-based surveillance project obtained accurate data on meningitis in a population of 34 million people during 1986, suggesting that improvements in early detection and antibiotic treatment may have occurred since that time.
Dexamethasone in adults with bacterial meningitis.
Background: Even when bacterial meningitis is diagnosed and treated promptly, it causes significant morbidity and mortality in adults. Dexamethasone, which lessens cerebrospinal inflammation, has
...
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