Acute, subchronic and chronic safety studies with genistein in rats.

  title={Acute, subchronic and chronic safety studies with genistein in rats.},
  author={R Michael McClain and Erich Wolz and Alberto Davidovich and Friedlieb Pfannkuch and James Adrian Edwards and Jochen Bausch},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  volume={44 1},
Genistein is a phytoestrogen that occurs naturally in the diet, especially in soy based foods. There is wide spread interest in phytoestrogens as chemopreventive agents for a variety of diseases and cancers based on epidemiologic evidence. Although soy, and its constituents such as genistein, have been consumed at high levels in several Asian populations without apparent adverse effects, concern has been raised about potential adverse effects due to the estrogenic and other activities. Safety… CONTINUE READING


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